Ceftriaxone resistance and genes encoding extended-spectrum β-lactamase among non-typhoidal Salmonella species from a tertiary care hospital in Kuala Lumpur, Malaysia.

نویسندگان

  • Rina Karunakaran
  • Sun Tee Tay
  • Fairuz Fadzilah Rahim
  • Bee Bee Lim
  • I-Ching Sam
  • Maria Kahar-Bador
  • Hamimah Hassan
  • Savithri Devi Puthucheary
چکیده

The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum β-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008-2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7% (2/74) in 2008, 4.0% (3/75) in 2009, and 3.4% (5/149) overall. CTX-M ESBL genes were detected in 2 of the 5 ceftriaxone-resistant isolates. The prevalence of ceftriaxone resistance, although low, is a concern because it limits therapeutic options. Continued surveillance of ceftriaxone resistance is important to monitor its trends.

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منابع مشابه

Ceftriaxone Resistance and Genes Encoding Extended-Spectrum b-Lactamase among Non-Typhoidal Salmonella Species from a Tertiary Care Hospital in Kuala Lumpur, Malaysia

The prevalence of ceftriaxone resistance and the associated genes encoding extended-spectrum b-lactamase (ESBL) was determined in 149 non-duplicate non-typhoidal Salmonella isolated in 2008–2009 from patients in a tertiary care hospital in Kuala Lumpur, Malaysia. The resistance rate to ceftriaxone was 2.7z (2/74) in 2008, 4.0z (3/75) in 2009, and 3.4z (5/149) overall. CTX-M ESBL genes were dete...

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عنوان ژورنال:
  • Japanese journal of infectious diseases

دوره 65 5  شماره 

صفحات  -

تاریخ انتشار 2012